Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
نویسندگان
چکیده
Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and immunohistochemical analysis revealed tissue consistent with neuroendocrine carcinoma. Despite complete medical workup, no other primary MCC could be detected. While being an atypical presentation, the tumor mass showed an excellent response to the combination of chemotherapy followed by radiotherapy.
منابع مشابه
Primary Pure Squamous Cell Carcinoma of Gallbladder Presenting as Acute Cholecystitis
Squamous cell carcinoma of the gallbladder is rare and constitutes only 0.5-3% of all malignancies of this organ. Most of the reported cases have had a component of adenocarcinoma. We report a 70-year-old man who presented with acute onset right upper quadrant pain. He operated on based on a presumptive diagnosis of acute cholecystitis according to clinical and ultrasonographic findings. Histop...
متن کاملPrimary Small Cell Carcinoma of the Esophagus (PSCEC) Associated with Paraneoplastic Sweating Syndrome: A Case Report and Literature Review
Introduction: Primary small cell carcinoma of theesophagus (PSCEC) associated with paraneoplastic sweating syndrome is a rare disease characterized with rapid growth rate, metastasis at the time of diagnosis, and poor prognosis. The lung is the most common site for small cell carcinoma but this malignancy includes 0.1% to 1% of all gastrointestinal and 0.8% to 2.7% of esophageal malignancies. ...
متن کاملPrimary Clear Cell Carcinoma with no Diethylstilbestrol Exposure; Case Series
One of the rare neoplasms of cervix uteri and vagina is clear cell carcinoma; mostly in patients with a positive past medical history of intrauterine diethylstilbestrol (DES) exposure which reveals the importance of other unknown risk factors of gynecologic neoplasms. 2 Asian women referred to the gynecology-oncology department. The first one came with a complaint of prolonged vaginal discharge...
متن کاملPrimary Intraosseous Carcinoma of the Maxilla
A primary intraosseous carcinoma (PIOC) is a squamous cell carcinoma arising within the jawbone andshould be differentiated from a malignant ameloblastoma. It is not due to arising from an odontogenic cyst or tumor. The possibility of the lesion being a metastasis fromanotherprimary site should be considered, and excluded by a careful history and examination. The diagnosis of a PIOC is ra...
متن کاملکارسینوماهای نورواندوکرین، بخش ایمونوهیستوشیمی انستیتو کانسر، 79-1375
Dispersed neuroendocrine system (D.N.S) consists of a wide variety of cells that are present in the central and peripheral nervous system and in many classic endocrine organs and different tissues such as respiratory and gastrointestinal tracts, skin, prostate, breast and also their neoplasm show neuroendocrine differentiation by electron microscopy, immunohistochemistry or biochemical techniqu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- World Journal of Surgical Oncology
دوره 5 شماره
صفحات -
تاریخ انتشار 2007